Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656187 | 1.00 | CTSS (0.51) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598248 | 0.93 | CTSS (0.51) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4597309 | 0.91 | SCN9A (0.42) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598875 | 0.91 | CTSS (0.52) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL4597933 | 0.90 | ANO1 (0.42) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598490 | 0.89 | CTSS (0.50) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL4598159 | 0.85 | CTSS (0.52) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL4924335 | 0.84 | CTSS (0.44) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4924346 | 0.84 | CTSS (0.44) | CTSSCTSKPTPN1SCN9AANO1 | |
| SCHEMBL4598158 | 0.84 | CTSS (0.52) | CTSSCTSKPTPN1SCN9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910274-A1 | PHENYL COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015807-A1 | PHENYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |