⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807213 | 1.00 | — | — | |
| SCHEMBL9807214 | 1.00 | — | — | |
| SCHEMBL1947771 | 1.00 | — | — | |
| SCHEMBL4656389 | 1.00 | — | — | |
| Acetic Acid SCHEMBL4126300 | 0.92 | APLNR (0.31) | — | |
| Acetic Acid SCHEMBL7676712 | 0.92 | APLNR (0.31) | — | |
| SCHEMBL9356674 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL16668279 | 0.76 | — | — | |
| SCHEMBL16668143 | 0.76 | — | — | |
| SCHEMBL9451089 | 0.76 | SPHK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049543-B1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | CALLAGHAN INNOVATION RES LTD (NZ) | 2014-11-05 | — | — | EP | disclosed |
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| US-8383636-B2 | Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-02-26 | — | — | US | disclosed |
| US-8383636-B2 | Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-02-26 | — | — | US | disclosed |
| EP-2395005-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | Industrial Research Limited (NZ) | 2011-12-14 | — | — | EP | disclosed |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | BIOCRYST PHARMACEUTICALS, INC. | 2011-06-02 | — | — | US | disclosed |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | BIOCRYST PHARMACEUTICALS, INC. | 2011-06-02 | — | — | US | disclosed |
| EP-2057165-B1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | IND RES LTD (NZ) | 2011-03-16 | — | — | EP | disclosed |
| US-20110046167-A1 | ACYCLIC AMINE INHIBITORS OF 5-METHYTIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2011-02-24 | — | — | US | disclosed |
| EP-0684948-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME. | DIAGNOSTIKFORSCHUNG INST (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |
| EP-0233249-B1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA | COOK IMAGING CORP (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5035877-A | Hydroxylated triiodo-isophthalamide derivative | COOK IMAGING CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |
| US-4954348-A | Non-ionic polyol contrast media from ionic contrast media | COOK IMAGING CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0233249-A4 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA. | COOK MANAGING INC (US) | 1988-10-06 | — | — | EP | disclosed |
| EP-0233249-A1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA. | COOK MANAGING INC (US) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987000757-A1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA | COOK IMAGING, INC. (US) | 1987-02-12 | — | — | WO | disclosed |