Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656147 | 0.94 | ECE1 (0.55) | ECE1ALDH1A1TSHRHTTNOTUM | |
| SCHEMBL4655406 | 0.94 | ECE1 (0.54) | ECE1ALDH1A1TSHRHTTNOTUM | |
| SCHEMBL4655358 | 0.93 | ECE1 (0.54) | ECE1ALDH1A1TSHRHTTNOTUM | |
| SCHEMBL4657644 | 0.91 | ECE1 (0.52) | ECE1NOTUMPTGDR2 | |
| SCHEMBL3569668 | 0.89 | KDM4E (0.53) | ECE1ALDH1A1TSHRHTTNOTUM | |
| SCHEMBL4656519 | 0.89 | ECE1 (0.54) | ECE1NOTUMPTGDR2RORC | |
| SCHEMBL4655399 | 0.89 | ECE1 (0.53) | ECE1PTGDR2 | |
| SCHEMBL4655387 | 0.89 | ECE1 (0.51) | ECE1RORC | |
| SCHEMBL3579347 | 0.86 | ECE1 (0.51) | ECE1NOTUMPTGDR2 | |
| SCHEMBL4655305 | 0.85 | ECE1 (0.46) | ECE1NOTUMPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |