Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 15/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579347 | 0.93 | ECE1 (0.51) | ECE1PTGDR2NOTUMCCR2 | |
| SCHEMBL4655305 | 0.92 | ECE1 (0.46) | ECE1PTGDR2NOTUMCCR2 | |
| SCHEMBL4655303 | 0.92 | ECE1 (0.49) | ECE1CCR2 | |
| SCHEMBL4656256 | 0.91 | ECE1 (0.62) | ECE1PTGDR2NOTUM | |
| SCHEMBL4656230 | 0.91 | ECE1 (0.60) | ECE1PTGDR2NOTUMCCR2 | |
| SCHEMBL15361984 | 0.90 | MAOB (0.48) | ECE1PTGDR2CCR2 | |
| SCHEMBL4655328 | 0.90 | PTGS2 (0.46) | ECE1PTGDR2CCR2 | |
| Hydrochloric Acid SCHEMBL3576467 | 0.90 | MAOB (0.47) | ECE1PTGDR2CCR2 | |
| SCHEMBL4656147 | 0.90 | ECE1 (0.55) | ECE1PTGDR2NOTUM | |
| SCHEMBL4655386 | 0.89 | ECE1 (0.51) | ECE1PTGDR2NOTUMCCR2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | claimed |
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |