SCHEMBL4656356

SCHEMBL4656356

CCCCCCCCCCCCCCCC1(C2(C(N)=O)CC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 7/20 0.37
EPHX1 P07099 1/20 0.37
MEN1 O00255 1/20 0.35
FAAH O00519 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
SOAT1 P35610 1/20 0.35
KMT2A Q03164 1/20 0.35
CES2 O00748 3/20 0.34
CES1 P23141 3/20 0.34
HSP90AA1 P07900 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11310382 1.00 SPHK1 (0.37) SPHK1EPHX1MEN1FAAHTP53
SCHEMBL11507313 0.75 GPR84 (0.35) EPHX1MEN1KMT2AALDH1A1TSHR
SCHEMBL5031163 0.75 CYP4F2 (0.41) SPHK1EPHX1MEN1FAAHTP53
SCHEMBL1044919 0.75 CYP4F2 (0.41) SPHK1EPHX1MEN1FAAHTP53
SCHEMBL7197775 0.75 CYP4F2 (0.41) SPHK1EPHX1MEN1FAAHTP53
SCHEMBL11506061 0.74 GPR84 (0.34) MEN1KMT2AALDH1A1TSHRSLC22A6
SCHEMBL613082 0.72 CYP4F2 (0.38) SPHK1EPHX1MEN1KMT2ACES2
SCHEMBL5038262 0.72 CETP (0.43) SPHK1EPHX1MEN1KMT2A
SCHEMBL5027335 0.72 CYP4F2 (0.46) SPHK1EPHX1MEN1KMT2A
SCHEMBL11864286 0.71 CETP (0.37) MEN1KMT2AALDH1A1TSHRSLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106272-B Fingerprint scratch resistant styrene-butadiene resin and preparation method thereof 广东众和高新科技有限公司 2023-10-13 CN claimed
CN-114106272-A Anti-scratch styrene-butadiene resin and preparation method thereof 广东众和高新科技有限公司 2022-03-01 CN claimed
US-20150050178-A1 Soft Magnetic Composite Materials THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-02-19 US claimed
WO-2013159558-A1 SOFT MAGNETIC COMPOSITE MATERIALS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2013-10-31 WO claimed
EP-0845492-B1 Thermoplastic polyurethanes containing special wax mixtures BAYER AG (DE) 2001-06-13 EP claimed
EP-0845492-A1 Thermoplastic polyurethanes containing special wax mixtures BAYER AG (DE) 1998-06-03 EP claimed
US-20220396655-A1 PROCESS FOR PREPARING POLYURETHANES HAVING A HIGH REACTION ENTHALPY COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-12-15 US disclosed
WO-2021122287-A1 METHOD FOR PRODUCING SEMI-CRYSTALLINE POLYURETHANES WITH A HIGH ENTHALPY OF REACTION COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO disclosed
WO-2021122279-A1 PROCESS FOR PREPARING POLYURETHANES HAVING A HIGH REACTION ENTHALPY COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO disclosed
EP-2760902-B1 HOMOGENEOUS EXTRUDED ARTICLES MADE FROM THERMOPLASTICALLY PROCESSABLE POLYURETHANES BASED ON POLYESTER DIOLS FORMED FROM SUCCINIC ACID AND 1,3-PROPANEDIOL COVESTRO DEUTSCHLAND AG (DE) 2018-08-08 EP disclosed
US-9458277-B2 Homogeneous extruded articles made from thermoplastically processable polyurethanes based on polyester diols formed from succinic acid and 1,3-propanediol COVESTRO DEUTSCHLAND AG (DE) 2016-10-04 US disclosed
US-20140256902-A1 HOMOGENEOUS EXTRUDED ARTICLES MADE FROM THERMOPLASTICALLY PROCESSABLE POLYURETHANES BASED ON POLYESTER DIOLS FORMED FROM SUCCINIC ACID AND 1,3-PROPANEDIOL BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-09-11 US disclosed
EP-2760902-A1 HOMOGENEOUS EXTRUDED ARTICLES MADE FROM THERMOPLASTICALLY PROCESSABLE POLYURETHANES BASED ON POLYESTER DIOLS FORMED FROM SUCCINIC ACID AND 1,3-PROPANEDIOL Bayer Intellectual Property GmbH (DE) 2014-08-06 EP disclosed
EP-0739946-A1 Preparation process for TPU-copolymer mixtures BAYER AG (DE) 1996-10-30 EP disclosed
EP-0571831-B1 Multi-stage process for the preparation of thermoplastically processable polyurethane elastomers BAYER AG (DE) 1996-10-23 EP disclosed
EP-0737718-A1 Preparation of TPU-copolymer-mixtures using flow improvers BAYER AG (DE) 1996-10-16 EP disclosed
EP-0696604-A1 Cycloaliphatic thermoplastic polyurethane elastomers BAYER AG (DE) 1996-02-14 EP disclosed
EP-0670339-A1 Process for the preparation of thermoplastic polyurethane elastomers (TPU) BAYER AG (DE) 1995-09-06 EP disclosed
EP-0571828-A2 Multi-stage process for the preparation of thermoplastically processable polyurethane elastomers BAYER AG (DE) 1993-12-01 EP disclosed
EP-0571831-A2 Multi-stage process for the preparation of thermoplastically processable polyurethane elastomers BAYER AG (DE) 1993-12-01 EP disclosed