Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 15/20 | 0.48 |
| ▸ | CHUK | O15111 | 2/20 | 0.48 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657007 | 0.92 | SLC6A3 (0.52) | SLC6A3TMEM97IKBKBCHUKEPHA3 | |
| SCHEMBL4659135 | 0.87 | IKBKB (0.51) | SLC6A3TMEM97IKBKBCHUKEPHA3 | |
| SCHEMBL4657084 | 0.85 | IKBKB (0.66) | SLC6A3TMEM97IKBKBCHUKEPHA3 | |
| SCHEMBL4657748 | 0.82 | IKBKB (0.50) | IKBKBCHUKEPHA3GAKICAM1 | |
| SCHEMBL4657934 | 0.80 | IKBKB (0.53) | IKBKBCHUKEPHA3GAKICAM1 | |
| SCHEMBL4657206 | 0.79 | IKBKB (0.44) | SLC6A3TMEM97IKBKBCHUKEPHA3 | |
| SCHEMBL4659402 | 0.79 | IKBKB (0.44) | IKBKBCHUKEPHA3GAKICAM1 | |
| SCHEMBL4657927 | 0.79 | IKBKB (0.44) | IKBKBCHUKEPHA3GAKICAM1 | |
| SCHEMBL4656552 | 0.78 | IKBKB (0.45) | SLC6A3TMEM97IKBKBCHUKEPHA3 | |
| SCHEMBL4656940 | 0.78 | IKBKB (0.69) | IKBKBCHUKEPHA3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513516-B1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMA (US) | 2008-12-03 | — | — | EP | claimed |