Tert-Butyl Hydroperoxide

Tert-Butyl Hydroperoxide

SCHEMBL4657003

CC(C)(C)OO.CC(C)c1ccc(OO)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HIF1A Q16665 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
TYR P14679 2/20 0.36
HTT P42858 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36
IDO1 P14902 2/20 0.35
ELANE P08246 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373970 0.90 RAB9A (0.39) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
SCHEMBL16628 0.89 RAB9A (0.46) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
SCHEMBL18614728 0.89 RAB9A (0.46) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
Tert-Butyl Hydroperoxide SCHEMBL7636785 0.88 RAB9A (0.40) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
Methyl Alcohol SCHEMBL7601547 0.87 RAB9A (0.44) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
Bicarbonate SCHEMBL11150406 0.81 RAB9A (0.49) KMT2ARAB9AMEN1SMN1; SMN2CYP2D6
Formaldehyde SCHEMBL8074512 0.81 RAB9A (0.44) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
Acetone SCHEMBL11207944 0.81 RAB9A (0.49) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2
Isopropylbenzene SCHEMBL4795495 0.81 MEN1 (0.46) KMT2ARAB9AMEN1RXRARXRB
SCHEMBL9244544 0.81 TSHR (0.52) KMT2ARAB9AMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679735-A USING PROTECTIVE COLLOID AS STABILIZER HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-21 US claimed
EP-2088468-B1 Method of preparing lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-1414873-B1 ENHANCED POLYMERIZATION PROCESS SABIC INNOVATIVE PLASTICS IP (NL) 2008-12-03 EP disclosed
EP-1792909-A1 Synthesis of polynucleotides Agilent Technologies, Inc. (US) 2007-06-06 EP disclosed
EP-1470175-B1 OLIGOMERIC CHAIN EXTENDERS FOR PROCESSING, POST-PROCESSING AND RECYCLING OF CONDENSATION POLYMERS, SYNTHESIS, COMPOSITIONS AND APPLICATIONS BASF CORP (US) 2007-03-14 EP disclosed
US-6784253-B2 IMPROVING IMPACT STRENGTH OF AN ABS GRAFT POLYMER, REDUCING MONOMER EMISSIONS IN THE PROCESS, INCREASE IN CROSSLINK DENSITY, BY GRAFT POLYMERIZATION A CROSSLINKED POLYBUTADIENE WITH STYRENE AND ACRYLONITRILE GENERAL ELECTRIC COMPANY 2004-08-31 US disclosed
EP-1414873-A1 ENHANCED POLYMERIZATION PROCESS GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
US-20040059079-A1 Adding a batch of water, an emulsifier, and a diene monomer to a reaction system to 40-80% full, adding a liquid feed of a diene monomer, an initiator and a chain transfer agent continuously and reacting; semi-batch process GENERAL ELECTRIC COMPANY 2004-03-25 US disclosed
WO-2003010214-A1 ENHANCED POLYMERIZATION PROCESS GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
EP-0850894-B1 Cement additive, its production process and use NIPPON CATALYTIC CHEM IND (JP) 2002-03-13 EP disclosed
EP-0590988-B1 Process for producing crosslinked polymer containing carboxyl group SUMITOMO SEIKA CHEMICALS (JP) 1997-07-02 EP disclosed
WO-1997022751-A2 PROCESS FOR REMOVING INKS FROM WASTE PAPER RHONE-POULENC INC. (US) 1997-06-26 WO disclosed
EP-0359796-A1 THERMOSETTING COMPOSITION FROM MALEIMIDE, OLEFINIC MONOMER AND UNSATURATED POLYESTER. ARISTECH CHEMICAL CORP (US) 1990-03-28 EP disclosed
WO-1989008670-A1 THERMOSETTING COMPOSITION FROM MALEIMIDE, OLEFINIC MONOMER AND UNSATURATED POLYESTER ARISTECH CHEMICAL CORPORATION (US) 1989-09-21 WO disclosed
US-4593081-A Acrylated ester PHILLIPS PETROLEUM COMPANY (US) 1986-06-03 US disclosed
EP-0025200-B1 PROCESS FOR PREPARING POLYPHENYLENE OXIDE GRAFT COPOLYMERS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-04 EP disclosed
US-4426459-A SWELLING, HYDROPEROXIDE, ALKALINE COMPOUND BRIDGESTONE TIRE CO., LTD. (JP) 1984-01-17 US disclosed
EP-0001561-A1 Water-soluble phosphorus containing carboxylic polymers The B.F. GOODRICH Company (US) 1979-05-02 EP disclosed
US-4071679-A WITH CONJUGATED DIENES PHILLIPS PETROLEUM COMPANY (US) 1978-01-31 US disclosed
US-3991243-A CROSSLINKING RAYCHEM CORPORATION (US) 1976-11-09 US disclosed