SCHEMBL4657010

SCHEMBL4657010

CCN(CC(=O)O)C(=O)C(CS)NC(=O)CCC(N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.56
GSTK1 Q9Y2Q3 1/20 0.56
NOD1 Q9Y239 12/20 0.47
GLO1 Q04760 1/20 0.45
FOLH1 Q04609 2/20 0.40
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GSR P00390 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRIK1 P39086 1/20 0.38
GRM5 P41594 1/20 0.38
GRIA1 P42261 1/20 0.38
GRIA2 P42262 1/20 0.38
GRIA3 P42263 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
GRIA4 P48058 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332934 0.92 PTGS1 (0.61) PTGS1GSTK1NOD1GLO1FOLH1
SCHEMBL3796919 0.90 PTGS1 (0.54) PTGS1GSTK1NOD1GLO1FOLH1
SCHEMBL993262 0.90 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1FOLH1
SCHEMBL5062960 0.89 PTGS1 (0.55) PTGS1GSTK1NOD1GLO1FOLH1
SCHEMBL3388582 0.89 PTGS1 (0.57) PTGS1GSTK1NOD1GLO1FOLH1
SCHEMBL3798413 0.88 NOD1 (0.52) PTGS1GSTK1NOD1GLO1
SCHEMBL2045164 0.87 NOD1 (0.54) PTGS1GSTK1NOD1GLO1
SCHEMBL6677046 0.87 NOD1 (0.54) PTGS1GSTK1NOD1GLO1
SCHEMBL2787322 0.86 NOD1 (0.56) PTGS1GSTK1NOD1GLO1
SCHEMBL3796642 0.86 NOD1 (0.56) PTGS1GSTK1NOD1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 EP claimed
WO-2002100811-A1 S-METHYLCYSTEINE S-ETHYLCYSTEINE AND RELATED S-ALKYLTHIOLS AS ANTAGONISTS TO THE EFFECTS OF S-NITROSOTHIOLS AND NITRIC OXIDE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2002-12-19 WO claimed
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 EP disclosed
EP-1853292-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER Gernot, Treusch (ES) 2007-11-14 EP disclosed
WO-2006084768-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2006-08-17 WO disclosed
WO-2002100811-A1 S-METHYLCYSTEINE S-ETHYLCYSTEINE AND RELATED S-ALKYLTHIOLS AS ANTAGONISTS TO THE EFFECTS OF S-NITROSOTHIOLS AND NITRIC OXIDE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2002-12-19 WO disclosed
EP-0514451-A1 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS. UNIV TEXAS (US) 1992-11-25 EP disclosed
WO-1991011117-A2 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-08-08 WO disclosed