Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389874 | 0.88 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL22657151 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL22445230 | 0.71 | — | — | |
| SCHEMBL28706249 | 0.71 | — | — | |
| SCHEMBL28704522 | 0.71 | TLR8 (0.34) | KMT2A | |
| SCHEMBL1085974 | 0.71 | CYP19A1 (0.42) | CYP19A1KMT2A | |
| SCHEMBL28218621 | 0.69 | CYP19A1 (0.45) | CYP19A1KMT2A | |
| SCHEMBL22445382 | 0.69 | DNM2 (0.31) | — | |
| SCHEMBL6078557 | 0.69 | MAPK1 (0.47) | — | |
| SCHEMBL22445475 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871749-A1 | 1H-QUINAZ0LINE-2,4-DIONES AND THEIR USE AS AMPA-RECEPTOR LIGANDS | Novartis AG (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108591-A1 | 1H-QUINAZ0LINE-2,4-DIONES AND THEIR USE AS AMPA-RECEPTOR LIGANDS | NOVARTIS AG (CH) | 2006-10-19 | — | — | WO | disclosed |