Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657977 | 0.87 | FFAR1 (0.57) | FFAR1RAB9ANPC1NR1H4LTA4H | |
| SCHEMBL4658325 | 0.87 | FFAR1 (0.57) | FFAR1RAB9ANPC1NR1H4LTA4H | |
| SCHEMBL4656941 | 0.87 | NPC1 (0.53) | KMT2AALDH1A1MEN1LMNAHPGD | |
| SCHEMBL4658315 | 0.86 | FFAR1 (0.58) | FFAR1RAB9ANPC1NR1H4LTA4H | |
| SCHEMBL4656989 | 0.85 | FFAR1 (0.55) | ALDH1A1HPGDFFAR1NR1H4LTA4H | |
| SCHEMBL4657178 | 0.84 | FFAR1 (0.54) | KMT2AMEN1FFAR1RAB9ANPC1 | |
| SCHEMBL4657145 | 0.84 | FFAR1 (0.54) | KMT2AALDH1A1HPGDFFAR1RAB9A | |
| SCHEMBL4657896 | 0.84 | FFAR1 (0.54) | KMT2AMEN1FFAR1RAB9ANPC1 | |
| SCHEMBL4656826 | 0.84 | FFAR1 (0.54) | KMT2AMEN1FFAR1RAB9ANR1H4 | |
| SCHEMBL4658399 | 0.84 | FFAR1 (0.54) | FFAR1RAB9ANR1H4LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391199-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2008-12-10 | — | — | EP | claimed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | claimed |
| US-20040224941-A1 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-11 | — | — | US | claimed |
| EP-1391199-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-02-25 | — | — | EP | claimed |
| EP-1391199-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-04-19 | — | — | US | disclosed |
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-04-19 | — | — | US | disclosed |
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-04-19 | — | — | US | disclosed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-7179817-B2 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-20040224941-A1 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-11 | — | — | US | disclosed |
| EP-1391199-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088027-A1 | Carboxylic acid derivatives and pharmaceutical compositions comprising the same as an active ingredient | EDF1, FFAR1, EDNRA | KMT2A 4772/4885ALDH1A1 411/4885MEN1 1748/4885 |
| US-20040224941-A1 | Carboxylic acid derivatives and drugs containing the same as the active ingredient | EDF1, FFAR1, VCAM1 | KMT2A 4829/4885ALDH1A1 261/4885MEN1 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.