Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.58 |
| ▸ | BRD2 | P25440 | 2/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513327 | 0.82 | HTT (0.59) | BRD4BRD2BRD3LMNAHTT | |
| SCHEMBL19667044 | 0.80 | MEN1 (0.67) | BRD4BRD2BRD3HTTMEN1 | |
| SCHEMBL10641824 | 0.80 | MEN1 (0.47) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL9174539 | 0.79 | CNR1 (0.46) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL128275 | 0.78 | ALDH1A1 (0.64) | BRD4BRD2BRD3LMNAHTT | |
| SCHEMBL18739953 | 0.78 | BRD4 (0.54) | BRD4BRD2BRD3LMNAHTT | |
| SCHEMBL4615963 | 0.77 | ALDH1A1 (0.57) | BRD4BRD2BRD3HTTMEN1 | |
| SCHEMBL8297692 | 0.77 | TP53 (0.63) | BRD4BRD2BRD3LMNAHTT | |
| SCHEMBL14615140 | 0.77 | TP53 (0.67) | BRD4BRD2BRD3LMNAHTT | |
| SCHEMBL6650873 | 0.77 | ALDH1A1 (0.54) | LMNAHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538070-B1 | PHARMACEUTICAL COMPOSITION OF BENZENESULFONAMIDE DERIVATIVES FOR TREATMENT OF ADENOID CYSTIC CARCINOMA | GONGWIN BIOPHARM CO LTD TAIWAN (TW) | 2023-03-29 | — | — | EP | claimed |
| EP-3468547-B1 | NOVEL BENZENESULFONAMIDE COMPOSITIONS FOR TREATMENT OF MALIGNANT PLEURAL EFFUSIONS | GONGWIN BIOPHARM CO LTD TAIWAN (TW) | 2021-10-06 | — | — | EP | claimed |
| EP-1389101-B1 | TOLUENE SULFONAMIDE-CONTAINING ANTI-TUMOR COMPOSITION AND METHOD OF USE THEREOF | PTS INTERNATIONAL INC (US) | 2008-12-03 | — | — | EP | claimed |
| EP-1764388-B1 | Composition, method of manufacturing a composition, heat-sensitive adhesive material, and information recording material | RICOH KK (JP) | 2008-10-29 | — | — | EP | claimed |
| EP-0894490-B1 | Cosmetic compositions comprising a film-forming polymer | OREAL (FR) | 2002-01-16 | — | — | EP | claimed |
| EP-0012521-B1 | VESICULAR RECORDING MATERIALS AND PROCESS FOR THEIR PRODUCTION | BEXFORD LIMITED (GB) | 1983-03-23 | — | — | EP | claimed |
| EP-1607452-B1 | Coating composition for improving for improving surface properties | DEGUSSA (DE) | 2006-08-30 | — | — | EP | disclosed |
| EP-1607452-A1 | Coating composition for improving for improving surface properties | Degussa AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| EP-1396523-A1 | Compacted flame retardant composition | Clariant GmbH (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-1396521-A1 | Low-dust powdered fire retardant composition, method for production and use thereof, and flameproof polymer moulding material | Clariant GmbH (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-1396522-A1 | Granular fire retardant composition | Clariant GmbH (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-0496120-B1 | Self-extinguishing, halogen-free flame retardant moulding composition with improved fire resistance | BASF AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0496120-A1 | Self-extinguishing, halogen-free flame retardant moulding composition with improved fire resistance | BASF Aktiengesellschaft (DE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0058331-B1 | POLYAMIDE MOULDING COMPOUNDS | BAYER AG (DE) | 1985-06-12 | — | — | EP | disclosed |
| EP-0058331-A1 | Polyamide moulding compounds | BAYER AG (DE) | 1982-08-25 | — | — | EP | disclosed |
| EP-0035669-A2 | Aqueous dispersions and process for making them | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |