Stearic Acid

Stearic Acid

SCHEMBL4657422

CCCCCCCCCCCCCCCCCC(=O)O.O.O

nearest known ligand 0.94

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.94
PPARG P37231 7/20 0.94
PPARD Q03181 7/20 0.94
PPARA Q07869 7/20 0.94
HDAC11 Q96DB2 5/20 0.94
TSHR P16473 4/20 0.94
PTPN1 P18031 3/20 0.94
FABP4 P15090 3/20 0.94
ALDH1A1 P00352 2/20 0.94
TLR2 O60603 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
KMT2A Q03164 2/20 0.94
ALOX15 P16050 2/20 0.94
HSD17B10 Q99714 2/20 0.94
SLC22A6 Q4U2R8 1/20 0.94
SLC22A8 Q8TCC7 1/20 0.94
MEN1 O00255 1/20 0.94
ESR1 P03372 1/20 0.94
PDE4A P27815 1/20 0.94
PDE3A Q14432 1/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecanoate SCHEMBL2153999 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Tridecanoate SCHEMBL29624615 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL11297381 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL3958653 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL1169126 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL31619587 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL8058964 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL717819 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL4967667 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL27814676 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7385068-B2 Stearate composition and method MALLINCKRODT INC. (US) 2008-06-10 US claimed
CN-1988890-A Improved stearate composition and preparation method MALLINCKRODT INC (US) 2007-06-27 CN claimed
EP-1781259-A2 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT, INC. (US) 2007-05-09 EP claimed
US-20060281937-A1 Stearate composition and method SpecGx LLC 2006-12-14 US claimed
WO-2006023035-A2 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT INC. (US) 2006-03-02 WO claimed
US-11219665-B2 Method for preparing a bone protein preparation and a bone protein preparation BBS-BIOACTIVE BONE SUBSTITUTES OYJ (FI) 2022-01-11 US disclosed
US-20200289617-A1 METHOD FOR PREPARING A BONE PROTEIN PREPARATION AND A BONE PROTEIN PREPARATION BBS-BIOACTIVE BONE SUBSTITUTES OYJ (FI) 2020-09-17 US disclosed
US-10702584-B2 Method for preparing a bone protein preparation and a bone protein preparation BBS-BIOACTIVE BONE SUBSTITUTES OYJ (FI) 2020-07-07 US disclosed
US-20150202265-A1 METHOD FOR PREPARING A BONE PROTEIN PREPARATION AND A BONE PROTEIN PREPARATION BBS-BIOACTIVE BONE SUBSTITUTES OY (FI) 2015-07-23 US disclosed
EP-1663165-B1 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT INC (US) 2008-12-03 EP disclosed
US-7456306-B2 Stearate composition and method of production thereof MALLINCKRODT INC (US) 2008-11-25 US disclosed
US-7385068-B2 Stearate composition and method MALLINCKRODT INC. (US) 2008-06-10 US disclosed
US-20060281937-A1 Stearate composition and method SpecGx LLC 2006-12-14 US disclosed
US-20060247456-A1 Stearate composition and method of production thereof SpecGx LLC 2006-11-02 US disclosed
CN-1829500-A Improved stearate composition and preparation method MALLINCKRODT INC (US) 2006-09-06 CN disclosed
EP-1663165-A2 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT, INC. (US) 2006-06-07 EP disclosed
WO-2006023035-A2 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT INC. (US) 2006-03-02 WO disclosed
WO-2005011641-A2 IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF MALLINCKRODT, INC. (US) 2005-02-10 WO disclosed
US-5856002-A Polymeric foam with antibacterial and mildewproofing functions MORI SHOJI (JP) 1999-01-05 US disclosed
US-3994855-A REACTION PRODUCT OF MANDELIC ACID AND IRON HYDROXYSTEARATE AB AKERLUND & RAUSING (SW) 1976-11-30 US disclosed