Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660857 | 0.87 | KMT2A (0.38) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2959697 | 0.87 | CCNT1 (0.38) | CCNT1CDK9KMT2AMEN1MAPT | |
| SCHEMBL2954806 | 0.85 | KMT2A (0.33) | CCNT1CDK9KMT2AMEN1MAPT | |
| SCHEMBL2957792 | 0.81 | ACHE (0.43) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2953761 | 0.80 | KMT2A (0.37) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2960067 | 0.80 | KMT2A (0.40) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2957660 | 0.78 | CPT1A (0.41) | CCNT1CDK9KMT2AMEN1MAPT | |
| SCHEMBL2957810 | 0.78 | KCNQ1 (0.40) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2948289 | 0.77 | TLR9 (0.42) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2953795 | 0.77 | KMT2A (0.39) | KMT2AMEN1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771425-B1 | 2-CARBAMIDE-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2008-05-14 | — | — | EP | claimed |
| EP-1771425-A1 | 2-CARBAMIDE-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006016039-A1 | 2-CARBAMIDE-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-02-16 | — | — | WO | disclosed |