Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578413 | 0.92 | ALDH1A1 (0.48) | PPARGALDH1A1PDCD1CD274LMNA | |
| SCHEMBL4657479 | 0.88 | PPARG (0.39) | PPARGALDH1A1PDCD1CD274LMNA | |
| SCHEMBL3565974 | 0.88 | PPARG (0.59) | PPARGALDH1A1PDCD1CD274LMNA | |
| SCHEMBL4658819 | 0.84 | PPARG (0.54) | PPARGALDH1A1PDCD1CD274LMNA | |
| SCHEMBL3570960 | 0.78 | PPARG (0.62) | PPARGALDH1A1TSHRRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3574111 | 0.77 | PPARG (0.61) | PPARGALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL13316128 | 0.76 | PPARG (0.74) | PPARG | |
| SCHEMBL4658548 | 0.76 | PPARG (0.76) | PPARG | |
| SCHEMBL4656720 | 0.75 | PPARG (0.69) | PPARGALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL3572873 | 0.73 | PPARG (0.79) | PPARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |