Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635532 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1635983 | 0.93 | MAPT (0.47) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1634840 | 0.85 | ABCG2 (0.40) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL1634855 | 0.85 | KMT2A (0.52) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1634857 | 0.85 | KMT2A (0.52) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3231497 | 0.84 | MEN1 (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1634386 | 0.83 | ABCG2 (0.43) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1635394 | 0.83 | PLK1 (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1635404 | 0.83 | ABCG2 (0.42) | ALDH1A1MAPTHTTLMNAGAA | |
| SCHEMBL1635408 | 0.83 | ABCG2 (0.42) | ALDH1A1MAPTHTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740530-A4 | SUBSTITUTED PHENOXY- AND PHENYLTHIO- DERIVATIVES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2008-02-27 | — | — | EP | claimed |
| JP-2007529530-A | — | — | 2007-10-25 | — | — | JP | claimed |
| EP-1740530-A2 | SUBSTITUTED PHENOXY- AND PHENYLTHIO- DERIVATIVES FOR TREATING PROLIFERATIVE DISORDERS | Temple University of the Commonwealth System of Higher Education (US) | 2007-01-10 | — | — | EP | claimed |
| WO-2005089269-A2 | SUBSTITUTED PHENOXY- AND PHENYLTHIO- DERIVATIVES FOR TREATING PROLIFERATIVE DISORDERS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2005-09-29 | — | — | WO | claimed |