Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808617 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL4526840 | 0.82 | ALDH1A1 (0.33) | ALDH1A1EPAS1 | |
| SCHEMBL8600753 | 0.80 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2007521 | 0.80 | ALDH1A1 (0.32) | ALDH1A1HSD11B1 | |
| SCHEMBL13464122 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL6688863 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL6277727 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL31159659 | 0.78 | CHRM1 (0.33) | ALDH1A1EPAS1 | |
| SCHEMBL11812840 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL11667113 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HSD11B1EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |