Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28740654 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL26747668 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL10136295 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL17002064 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12643425 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12643424 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL10615091 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL1741155 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL14819881 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12082030 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694630-B1 | METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2008-05-07 | — | — | EP | claimed |
| EP-0979071-B1 | MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS AND FOR DELIVERY OF DRUGS INTO THE BLOODSTREAM | POINT BIOMEDICAL CORP (US) | 2007-11-07 | — | — | EP | claimed |
| EP-1474384-A1 | BETA-AMINO KETONES FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068731-A1 | BETA-AMINO KETONES FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | disclosed |
| EP-0428440-B1 | Soluble, non-toxic derivatives of basic polyene macrolides, their preparation and use | MAYOLY SPINDLER (FR) | 1997-03-05 | — | — | EP | disclosed |
| WO-1991007421-A1 | NOVEL SOLUBLE AND NON-TOXIC DERIVATIVES OF BASIC POLYENIC MACROLIDES AND THEIR PREPARATION AND USE | MAYOLY-SPINDLER (FR) | 1991-05-30 | — | — | WO | disclosed |
| EP-0428440-A1 | Soluble, non-toxic derivatives of basic polyene macrolides, their preparation and use | MAYOLY-SPINDLER (FR) | 1991-05-22 | — | — | EP | disclosed |