Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28740654 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL26747668 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL17002064 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL4658553 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12643425 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12643424 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL10615091 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL1741155 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL14819881 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL12082030 | 0.98 | GRIK1 (0.52) | GRIK1GRIK2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150011466-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS INC (US) | 2015-01-08 | — | — | US | disclosed |
| US-20130210709-A1 | CXCR4 Receptor Compounds | ACER THERAPEUTICS INC. | 2013-08-15 | — | — | US | disclosed |
| US-20130005944-A1 | CXCR4 Receptor Compounds | ACER THERAPEUTICS INC. | 2013-01-03 | — | — | US | disclosed |
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2012-02-02 | — | — | US | disclosed |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | GRIK1 1040/4885GRIK2 1712/4885GNAI3 172/4885 |
| US-20150011466-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | GRIK1 1073/4885GRIK2 1148/4885GNAI3 51/4885 |
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | APLNR, AP1G1, AP2B1 | GRIK1 1113/4885GRIK2 1139/4885GNAI3 54/4885 |
| US-20130005944-A1 | CXCR4 Receptor Compounds | CXCL12, CXCR4, CCR5 | GRIK1 1567/4885GRIK2 2536/4885GNAI3 52/4885 |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | CXCR5, CXCR1, CCR5 | GRIK1 418/4885GRIK2 549/4885GNAI3 90/4885 |
| US-20130210709-A1 | CXCR4 Receptor Compounds | CXCR4, CXCL12, SDF4 | GRIK1 612/4885GRIK2 1035/4885GNAI3 65/4885 |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | CRHR1, CRH, CRHR2 | GRIK1 285/4885GRIK2 450/4885GNAI3 430/4885 |
| US-20160159861-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | GRIK1 1073/4885GRIK2 1148/4885GNAI3 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.