SCHEMBL465867

SCHEMBL465867

Cc1nc(NC2CC2)nc(NC(C)(C)C)n1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 3/20 0.39
PDE4A P27815 2/20 0.39
CYP2C19 P33261 2/20 0.39
MAPK8 P45983 2/20 0.38
MAPK9 P45984 1/20 0.38
KMT2A Q03164 3/20 0.37
CYP2C9 P11712 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2D6 P10635 1/20 0.37
IDH1 O75874 4/20 0.36
IDH2 P48735 1/20 0.36
ALOX15 P16050 1/20 0.36
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724202 0.85 NPSR1 (0.69) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL28161886 0.84 NPSR1 (0.52) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL10816110 0.84 SMN1; SMN2 (0.68) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL241791 0.81 NPSR1 (0.50) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL8489833 0.78 EPHX1 (0.36) NPSR1PDE4AIDH1IDH2
SCHEMBL8489830 0.78 EPHX1 (0.36) NPSR1PDE4AIDH1IDH2
SCHEMBL3499244 0.77 PDE4A (0.66) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL16657115 0.77 SMN1; SMN2 (0.54) SMN1; SMN2LMNAMAPTCYP1A2PDE4A
SCHEMBL12612965 0.77 NPSR1 (0.53) NPSR1SMN1; SMN2LMNAMAPTCYP1A2
SCHEMBL28328275 0.77 PDE4A (0.40) NPSR1PDE4ACYP2C19CYP2C9IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102202506-B Spinosyn antifouling compositions, methods of use thereof, and articles protected from attachment of biofouling organisms ENTARCO SA (GR) 2015-07-29 CN claimed
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
EP-0954966-B1 Polymeric controlled release compositions ROHM & HAAS (US) 2003-06-25 EP claimed
EP-0880892-B1 Controlled release compositions ROHM & HAAS (US) 2002-12-18 EP claimed
US-6221374-B1 BIOLOGICALLY ACTIVE COMPOUND, POLYPHENOLIC COMPOUND, ORGANIC SOLVENT CARRIER ROHM AND HAAS COMPANY 2001-04-24 US claimed
US-6090399-A POROUS MATRIX ROHM AND HAAS COMPANY (US) 2000-07-18 US claimed
EP-0954965-A1 Controlled release compositions ROHM AND HAAS COMPANY (US) 1999-11-10 EP claimed
EP-0954966-A1 Polymeric controlled release compositions ROHM AND HAAS COMPANY (US) 1999-11-10 EP claimed
EP-0922386-A2 Controlled release compositions ROHM AND HAAS COMPANY (US) 1999-06-16 EP claimed
US-5855654-A APPLYING (DIHYDRO)PYRIDAZINONE COMPOUND ROHM AND HAAS COMPANY (US) 1999-01-05 US claimed
EP-0880892-A1 Controlled release compositions ROHM AND HAAS COMPANY (US) 1998-12-02 EP claimed
US-5833742-A APPLYING ONTO OR INTO MARINE STRUCTURE A MICROBIOCIDES TO INHIBIT THE ORGANISM GROWTH ROHM AND HAAS COMPANY (US) 1998-11-10 US claimed
EP-0856255-A2 Pyridazinones as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-08-05 EP claimed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP claimed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP claimed
CN-107922571-B Antifouling composition 巴斯夫聚氨酯特种产品(中国)有限公司 2021-04-30 CN disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed