Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619199 | 0.82 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL465867 | 0.77 | NPSR1 (0.54) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL12883321 | 0.74 | MAPT (0.59) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL13588261 | 0.74 | NPSR1 (0.33) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL14438979 | 0.72 | PDE4A (0.78) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL11251263 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL9387084 | 0.70 | LMNA (1.00) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL6168317 | 0.70 | LMNA (0.90) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL10599233 | 0.70 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL14124529 | 0.69 | GAA (0.30) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550011-B2 | Surface coatings for biological implants and prostheses | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-9550011-B2 | Surface coatings for biological implants and prostheses | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-20150109573-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-23 | — | — | US | disclosed |
| US-20150109573-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-23 | — | — | US | disclosed |