Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.30 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864119 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL4351373 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL434782 | 0.79 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL8512816 | 0.79 | CYP1A2 (0.39) | SMN1; SMN2ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL4345812 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL4390427 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29463589 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL225440 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL4388462 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL4401169 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254922-B1 | Polyalkoxyalkyl (meth)acrylates and preparation thereof | TERUMO CORP (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-6737493-B2 | ANIONIC POLYMERIZED POLYALKOXYALKYL (METH)ACRYLATE, SUCH AS POLYMETHOXYETHYL ACRYLATE; MADE USING AN ARYLOXYALUMINUM COMPOUND AS CATALYST; USE SUCH AS ARTIFICIAL BODY PARTS, CATHETERS | TERUMO KABUSHIKI KAISHA (JP) | 2004-05-18 | — | — | US | disclosed |
| US-20020183472-A1 | Biocompatible material | TERUMO KABUSHIKI KAISHA (JP) | 2002-12-05 | — | — | US | disclosed |
| EP-1254922-A2 | Polyalkoxyalkyl (meth)acrylates and preparation thereof | TERUMO KABUSHIKI KAISHA (JP) | 2002-11-06 | — | — | EP | disclosed |