Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.69 |
| ▸ | GSK3B | P49841 | 4/20 | 0.69 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318940 | 0.81 | GSK3A (1.00) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL2085483 | 0.79 | GSK3A (0.69) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL20339296 | 0.77 | KMT2A (0.73) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL29558351 | 0.76 | GSK3A (0.65) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL4791747 | 0.76 | GSK3A (0.65) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL31114554 | 0.73 | POLB (0.60) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL2087485 | 0.72 | GSK3A (0.59) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL2087484 | 0.72 | GSK3A (0.59) | GSK3AGSK3BELANEF2PLG | |
| SCHEMBL10559302 | 0.72 | GSK3A (0.70) | GSK3AGSK3BELANEF2PLG | |
| Hydantoin SCHEMBL4914979 | 0.71 | GSK3A (0.77) | GSK3AGSK3BELANEF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004628-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | Universidade Federal de Pernambuco-Ufpe (BR) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007109871-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | UNIVERSIDADE FEDERAL DE PERNAMBUCO - UFPE (BR) | 2007-10-04 | — | — | WO | disclosed |
| WO-2004024058-A2 | MOLECULES WITH ANTITUMOR ACTIVITY AND CHEMICAL SYNTHESIS | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-03-25 | — | — | WO | disclosed |