Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.77 |
| ▸ | GSK3B | P49841 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318940 | 0.87 | GSK3A (1.00) | GSK3AGSK3BKMT2AMEN1ELANE | |
| Benzyl Alcohol SCHEMBL18894571 | 0.76 | TSHR (0.52) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL20339296 | 0.73 | KMT2A (0.73) | GSK3AGSK3BKMT2AMEN1ELANE | |
| Hydantoin SCHEMBL27574136 | 0.73 | CRBN (0.46) | DDB1CRBN | |
| SCHEMBL30953279 | 0.73 | GSK3A (0.71) | GSK3AGSK3BKMT2AMEN1GAA | |
| SCHEMBL6293317 | 0.73 | KMT2A (0.73) | GSK3AGSK3BKMT2AMEN1GAA | |
| Chlorobenzene SCHEMBL28430004 | 0.72 | TSHR (0.44) | GSK3AGSK3BKMT2AMEN1CMA1 | |
| SCHEMBL10559302 | 0.72 | GSK3A (0.70) | GSK3AGSK3BKMT2AMEN1ELANE | |
| Biphenyl SCHEMBL1712625 | 0.71 | TYRO3 (0.42) | GSK3AGSK3BGAASMN1; SMN2CRBN | |
| SCHEMBL4658933 | 0.71 | GSK3A (0.69) | GSK3AGSK3BKMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470703-B1 | Yohimbine derivatives and use thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-12-30 | — | — | US | disclosed |