Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499404 | 0.73 | ALDH1A1 (0.39) | MAOBRAB9AALDH1A1NPC1LMNA | |
| SCHEMBL4496175 | 0.72 | ESR1 (0.38) | MAOBRAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4505882 | 0.72 | CETP (0.41) | MAOBALDH1A1TP53RXFP1GCGR | |
| SCHEMBL4505879 | 0.72 | CETP (0.41) | MAOBALDH1A1TP53RXFP1GCGR | |
| SCHEMBL4497013 | 0.71 | CETP (0.41) | MAOBRAB9AALDH1A1NPC1LMNA | |
| SCHEMBL4504814 | 0.71 | CETP (0.36) | MAOBALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL4510672 | 0.69 | CETP (0.39) | GCGR | |
| SCHEMBL4503613 | 0.69 | CETP (0.34) | MAOBALDH1A1TP53RXFP1GCGR | |
| SCHEMBL4493258 | 0.69 | ALDH1A1 (0.35) | MAOBRAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4501378 | 0.68 | MAOB (0.38) | MAOBRAB9AALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999123-A1 | SUBSTITUTED CHROMANOL DERIVATIVES AND THEIR USE | Bayer HealthCare AG (DE) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007107243-A1 | SUBSTITUTED CHROMANOL DERIVATIVES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2007-09-27 | — | — | WO | disclosed |