SCHEMBL4659131

SCHEMBL4659131

CC(C)C1=Cc2c(-c3ccc4ccccc4c3)cccc2C1[Zr](Cl)(Cl)(C1C(C(C)C)=Cc2c(-c3ccc4ccccc4c3)cccc21)=[Si](C)C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
DHFR P00374 1/20 0.30
S1PR4 O95977 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240950 0.87
SCHEMBL1241164 0.86 GSTP1 (0.34) GSTP1SLC6A2SLC6A4SLC6A3HDAC4
SCHEMBL1238250 0.86 HTR2A (0.31) GSTP1SLC6A2SLC6A4SLC6A3S1PR4
SCHEMBL2512461 0.84 GSTP1 (0.33) GSTP1SLC6A2SLC6A4SLC6A3HDAC4
SCHEMBL1238125 0.84 GSTP1 (0.33) GSTP1SLC6A2SLC6A4SLC6A3HDAC4
SCHEMBL3686279 0.84
SCHEMBL1240242 0.84 NPC1 (0.31)
SCHEMBL1240254 0.83 HTR1A (0.31)
SCHEMBL1239988 0.83 GSTP1 (0.31) GSTP1
SCHEMBL15329121 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632532-B1 SOLVENT DISPERSION OF COMPOSITE RESIN AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-12-05 EP disclosed
US-8507603-B2 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2013-08-13 US disclosed
EP-1088836-B1 ETHYLENE/ALPHA-OLEFIN/UNCONJUGATED POLYENE COPOLYMER RUBBER, RUBBER COMPOSITION FOR SEALING, MOLDED RUBBER FOR SEALING, AND PROCESS FOR PRODUCING THE MOLDED RUBBER PART MITSUI CHEMICALS INC (JP) 2012-11-21 EP disclosed
US-20110054118-A1 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-03-03 US disclosed
EP-1640415-B1 Olefinic thermoplastic elastomer composition and method for producing the same MITSUI CHEMICALS INC (JP) 2008-12-17 EP disclosed
EP-1065241-B1 Olefinic thermoplastic elastomer composition and method for producing the same MITSUI CHEMICALS INC (JP) 2006-04-05 EP disclosed
EP-1640415-A2 Olefinic thermoplastic elastomer composition and method for producing the same MITSUI CHEMICALS, INC. (JP) 2006-03-29 EP disclosed
EP-1632532-A1 SOLVENT DISPERSION OF COMPOSITE RESIN AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2006-03-08 EP disclosed
US-6635727-B1 Random copolymer comprising structural units derived from comonomers of ethylene, one or more alpha-olefins, one or more trienes, and one or more non-conjugated polyenes in specified amounts and having specified intrinsic viscosity MITSUI CHEMICALS, INC. (JP) 2003-10-21 US disclosed
US-6635705-B2 Crosslinked crystalline polyolefin resin, an ethylene-alpha-olefin-non-conjugated polyene copolymer rubber, and polyisobutylene, butyl rubber or a propylene-ethylene copolymer MITSUI CHEMICALS, INC. (JP) 2003-10-21 US disclosed
US-6410650-B1 MOLDING MATERIALS MITSUI CHEMICALS INC (JP) 2002-06-25 US disclosed
US-20020055591-A1 Olefinic thermoplastic elastomer composition and method for producing the same MITSUI CHEMICALS, INC. 2002-05-09 US disclosed
EP-1152016-A1 ETHYLENE COPOLYMER RUBBER, PROCESS FOR PRODUCING THE SAME, AND USE Mitsui Chemicals, Inc. (JP) 2001-11-07 EP disclosed
EP-1088836-A1 ETHYLENE/ALPHA-OLEFIN/UNCONJUGATED POLYENE COPOLYMER RUBBER, RUBBER COMPOSITION FOR SEALING, MOLDED RUBBER FOR SEALING, AND PROCESS FOR PRODUCING THE MOLDED RUBBER Mitsui Chemicals, Inc. (JP) 2001-04-04 EP disclosed
EP-1065241-A2 Olefinic thermoplastic elastomer composition and method for producing the same Mitsui Chemicals, Inc. (JP) 2001-01-03 EP disclosed