Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660667 | 0.83 | HTR2A (0.40) | HTR2AHTR2C | |
| SCHEMBL4661846 | 0.78 | HTR2A (0.39) | HTR2AHTR2C | |
| SCHEMBL132568 | 0.77 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL4724070 | 0.76 | HTR2A (0.51) | HTR2AHTR2C | |
| SCHEMBL4659255 | 0.72 | DRD1 (0.40) | HTR2AHTR2C | |
| SCHEMBL1558307 | 0.72 | MAPT (0.41) | — | |
| SCHEMBL12391712 | 0.72 | HTR2A (0.38) | HTR2AHTR2C | |
| SCHEMBL28796143 | 0.71 | HTR2C (0.50) | HTR2AHTR2C | |
| SCHEMBL5578058 | 0.71 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL4660682 | 0.71 | HTR2A (0.76) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004627-A2 | 3-PYRIDINYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120600-A2 | 3-PYRIDINYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007120600-A2 | 3-PYRIDINYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |