SCHEMBL4659461

SCHEMBL4659461

C/C(=C/F)Cc1cccc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
MAOB P27338 7/20 0.44
TAAR1 Q96RJ0 4/20 0.43
EGFR P00533 3/20 0.43
ERBB2 P04626 3/20 0.43
HCAR2 Q8TDS4 1/20 0.42
MAOA P21397 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660555 1.00 IDO1 (0.46) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL27259067 0.85 IDO1 (0.48) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL4659432 0.80 IDO1 (0.47) IDO1AGXTMAOBTAAR1HCAR2
SCHEMBL9007016 0.79 TAAR1 (0.41) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL9294120 0.79 TAAR1 (0.50) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL4660671 0.79 HTR3E (0.51) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL9006997 0.78 TAAR1 (0.40) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL4660670 0.76 CTBP2 (0.54) IDO1AGXTMAOBTAAR1
SCHEMBL1294723 0.76 TAAR1 (0.49) IDO1AGXTMAOBTAAR1EGFR
SCHEMBL1294722 0.76 TAAR1 (0.49) IDO1AGXTMAOBTAAR1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004166-A2 INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES LA JOLLA PHARMACEUTICAL COMPANY (US) 2008-12-24 EP claimed
WO-2007120528-A2 INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES LA JOLLA PHARMACEUTICAL COMPANY (US) 2007-10-25 WO claimed