SCHEMBL465976

SCHEMBL465976

C=CC/C(C)=C/CCCC(=C)C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
FNTA P49354 3/20 0.33
FNTB P49356 3/20 0.33
KMT2A Q03164 2/20 0.33
LSS P48449 1/20 0.33
SQLE Q14534 3/20 0.31
ALOX15 P16050 2/20 0.31
PGGT1B P53609 1/20 0.31
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
UGT1A1 P22309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465977 1.00 TSHR (0.34) TSHRFNTAFNTBKMT2ALSS
SCHEMBL1305497 0.85 KMT2A (0.41) TSHRFNTAFNTBKMT2ASQLE
SCHEMBL1305499 0.85 KMT2A (0.41) TSHRFNTAFNTBKMT2ASQLE
SCHEMBL1486008 0.80 KMT2A (0.34) TSHRKMT2ASQLEALOX15MAPT
SCHEMBL139284 0.79
SCHEMBL847130 0.77 TSHR (0.52) TSHRFNTAFNTBKMT2ALSS
SCHEMBL847131 0.77 TSHR (0.52) TSHRFNTAFNTBKMT2ALSS
SCHEMBL7939611 0.77 TSHR (0.50) TSHRKMT2ASQLEALOX15MAPT
SCHEMBL1269881 0.75 KMT2A (0.31) KMT2A
SCHEMBL11762052 0.75 ALDH1A1 (0.40) FNTAFNTBKMT2ASQLEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344583-B1 POLYMER BLENDS WITH ETHYLENE/ALPHA-OLEFIN INTERPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-05 EP disclosed
EP-2658919-B1 THERMOPLASTIC VULCANIZATE COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-25 EP disclosed
EP-1858942-B1 POLYMER BLENDS FROM INTERPOLYMER OF ETHYLENE/ALPHA-OLEFIN WITH IMPROVED COMPATIBILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-13 EP disclosed
US-9309396-B2 Thermoplastic vulcanizate composition, method of producing the same, and articles made therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-12 US disclosed
US-8921491-B2 Polymer blends with ethylene/α-olefin interpolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-30 US disclosed
EP-2055458-B1 PELLETS COMPRISING POLYMER MITSUI CHEMICALS INC (JP) 2014-10-01 EP disclosed
US-8617706-B2 Pellets comprising polymer and package containing the same MITSUI CHEMICALS, INC. (JP) 2013-12-31 US disclosed
US-20130324658-A1 Thermoplastic Vulcanizate Composition, Method of Producing the Same, and Articles Made Therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-05 US disclosed
EP-2658919-A1 THERMOPLASTIC VULCANIZATE COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM Dow Global Technologies LLC (US) 2013-11-06 EP disclosed
WO-2012088689-A1 THERMOPLASTIC VULCANIZATE COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-07-05 WO disclosed
US-7122584-B2 Flexible resin pellet and process for producing the same MITSUI CHEMICALS, INC. (JP) 2006-10-17 US disclosed
WO-2006101928-A2 THERMOPLASTIC VULCANIZATE COMPRISING INTERPOLYMERS OF ETHYLENE/α-OLEFINS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-28 WO disclosed
WO-2006101924-A2 POLYMER BLENDS FROM INTERPOLYMER OF ETHYLENE/ALPHA-OLEFIN WITH IMPROVED COMPATIBILITY DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-28 WO disclosed
US-20060199906-A1 Polymer blends from interpolymers of ethylene/alpha-olefin with improved compatibility DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060199910-A1 Thermoplastic vulcanizate comprising interpolymers of ethylene alpha-olefins DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
EP-1403313-A1 FLEXIBLE RESIN PELLET AND PROCESS FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2004-03-31 EP disclosed
WO-2003082971-A2 THERMOPLASTIC VULCANIZATE COMPOSITION AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2003-10-09 WO disclosed
US-20030181553-A1 Flexible resin pellet and process for producing the same MITSUI CHEMICALS, INC. (JP) 2003-09-25 US disclosed
US-4111897-A ETHYLENE-OLEFIN-POLYENE TERPOLYMER ELASTOMER, CARBON BLACK, PENTACHLOROTHIOPHENOL OR SALTS THE B. F. GOODRICH COMPANY (US) 1978-09-05 US disclosed
US-4008190-A Vulcanizates of EPDM and diene rubber blends THE B. F. GOODRICH COMPANY (US) 1977-02-15 US disclosed