Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660066 | 0.92 | PDE4D (0.43) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL4660062 | 0.92 | PDE4D (0.43) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL4660107 | 0.84 | ALPL (0.43) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL4659962 | 0.81 | PDE4D (0.43) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL4659922 | 0.72 | ALPL (0.42) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL5433411 | 0.71 | MEN1 (0.41) | SMN1; SMN2KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL5435957 | 0.71 | MEN1 (0.41) | SMN1; SMN2KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL4661303 | 0.71 | PDE4D (0.44) | PDE4DSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL4660016 | 0.71 | KDM4E (0.38) | KMT2AKDM4EMEN1LMNARAB9A | |
| SCHEMBL5427021 | 0.71 | ESR1 (0.44) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |