SCHEMBL4660272

SCHEMBL4660272

CCCCOc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.70
ALDH1A1 P00352 3/20 0.70
MAPT P10636 2/20 0.70
KMT2A Q03164 2/20 0.70
HPGD P15428 3/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
RECQL P46063 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NR1H4 Q96RI1 1/20 0.48
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CYP2D6 P10635 1/20 0.44
SLC6A2 P23975 1/20 0.44
PDE4A P27815 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
HRH1 P35367 1/20 0.44
HTT P42858 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660398 0.96 LMNA (0.68) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661617 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4660278 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4662829 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661658 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4660309 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661746 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661584 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661735 0.95 LMNA (0.67) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL4661580 0.94 LMNA (0.71) LMNAALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102247303-A Organic-inorganic self-assembled ultraviolet absorbent and preparation method thereof UNIV SHANGHAI 2011-11-23 CN claimed
CN-102247303-A Organic-inorganic self-assembled ultraviolet absorbent and preparation method thereof UNIV SHANGHAI 2011-11-23 CN disclosed
EP-1427697-B1 SULPHONATION OF PHENOLS GREAT LAKES CHEMICAL EUROP (CH) 2008-12-24 EP disclosed
CN-1239477-C Sulphonation of phenols GREAT LAKES CHEMICAL EUROP (CH) 2006-02-01 CN disclosed
US-6936732-B2 Sulphonation of phenols ADDIVANT USA, LLC 2005-08-30 US disclosed
US-20050054876-A1 Sulphonation of phenols ADDIVANT USA, LLC 2005-03-10 US disclosed
CN-1556792-A Sulphonation of phenols �����ѧ��˾ŷ�޷ֹ�˾ 2004-12-22 CN disclosed
EP-1427697-A1 SULPHONATION OF PHENOLS Great Lakes Chemical (Europe) GmbH (CH) 2004-06-16 EP disclosed
WO-2003027063-A1 SULPHONATION OF PHENOLS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2003-04-03 WO disclosed
EP-0351615-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF Aktiengesellschaft (DE) 1992-10-28 EP disclosed
US-5072034-A PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
EP-0351615-A1 Process for the preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids BASF Aktiengesellschaft (DE) 1990-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054876-A1 Sulphonation of phenols CBR3, C1S, C1R LMNA 3440/4885ALDH1A1 3616/4885MAPT 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.