SCHEMBL4660280

SCHEMBL4660280

O=C(O)C(=O)Cc1cc2ccccc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.53
NLRP3 Q96P20 1/20 0.52
KDM4E B2RXH2 3/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
DAO P14920 1/20 0.51
SRD5A2 P31213 1/20 0.51
HSD17B10 Q99714 1/20 0.51
IDO1 P14902 1/20 0.51
MTNR1A P48039 1/20 0.51
MTNR1B P49286 1/20 0.51
FLT3 P36888 1/20 0.49
ADAMTS4 O75173 1/20 0.48
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
MAPK1 P28482 1/20 0.46
AKR1B1 P15121 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383990 1.00 LOXL2 (0.53) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL29396052 0.95 AKR1B1 (0.49) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL49270 0.86 LOXL2 (0.56) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL31336079 0.86 LOXL2 (0.56) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL29365671 0.86 LOXL2 (0.56) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL31511816 0.84 LOXL2 (0.55) LOXL2NLRP3KDM4EMAPTHPGD
Water SCHEMBL30025993 0.84 LOXL2 (0.55) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL3451201 0.84 LOXL2 (0.58) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL24762573 0.83 LOXL2 (0.50) LOXL2NLRP3KDM4EMAPTHPGD
SCHEMBL3654751 0.83 LOXL2 (0.50) LOXL2NLRP3KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114674956-A Application of urine biomarker detection reagent in preparation of kit for predicting neuropsychiatric sequelae of new coronary pneumonia 重庆医科大学附属第一医院 2022-06-28 CN claimed
EP-0188712-B1 PROCESS FOR OBTAINING PHENYL ALANINE-CONTAINING MICROORGANISMS AND THEIR USE IN THE PREPARATION OF L-ALPHA-AMINO ACIDS Degussa Aktiengesellschaft (DE) 1990-01-31 EP claimed
EP-0120208-B1 MICROBIOLOGICALLY PRODUCED L-PHENYLALANIN-DEHYDROGENASE, PROCESS FOR OBTAINING IT AND ITS USE Degussa Aktiengesellschaft (DE) 1989-03-22 EP claimed
EP-0188712-A1 Process for obtaining phenyl alanine-containing microorganisms and their use in the preparation of L-alpha-amino acids Degussa Aktiengesellschaft (DE) 1986-07-30 EP claimed
US-4590161-A AEROBIC CULTIVATION OF BREUIBACTERIUM DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-05-20 US claimed
CN-119178831-A Optimized 3-nitrophenylhydrazine derivatization method and application 中国药科大学 2024-12-24 CN disclosed
CN-118141805-A Application of ergothioneine in preparation of medicine for treating autism spectrum disorder 深圳恩赞美科技有限公司 2024-06-07 CN disclosed
CN-118109531-A Method for synthesizing indole-3-pyruvic acid in vitro by using enzyme catalysis 安阳尼采启合生物科技有限公司 2024-05-31 CN disclosed
CN-117736926-A Saline-alkali resistant aeromonas Aeromonas bivalvium BM-B and application thereof 中国科学院遗传与发育生物学研究所农业资源研究中心 2024-03-22 CN disclosed
CN-111951898-B Method for screening enzyme capable of converting L-amino acid into 2-keto acid 中国科学院微生物研究所 2024-02-23 CN disclosed
CN-114569633-B Intestinal selective chelators for the treatment and prevention of autism and related disorders 轴向治疗公司 2023-11-17 CN disclosed
CN-115960720-A Microorganisms and methods for producing fatty alcohols of specific length and related compounds 基因组股份公司 2023-04-14 CN disclosed
US-5256551-A Heat-treating Escherichia in presence of ammonium compound RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1993-10-26 US disclosed
EP-0289796-B1 METHOD OF TREATING MICROORGANISM CELLS CONTAINING TRYPTOPHANASE OR TREATED PRODUCT THEREOF RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1992-10-21 EP disclosed
EP-0120208-B1 MICROBIOLOGICALLY PRODUCED L-PHENYLALANIN-DEHYDROGENASE, PROCESS FOR OBTAINING IT AND ITS USE Degussa Aktiengesellschaft (DE) 1989-03-22 EP disclosed
EP-0289796-A2 Method of treating microorganism cells containing tryptophanase or treated product thereof RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1988-11-09 EP disclosed
US-4622301-A DISINTEGRATION OF PROTEUS BASF AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
US-4590161-A AEROBIC CULTIVATION OF BREUIBACTERIUM DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed
US-4590161-A AEROBIC CULTIVATION OF BREUIBACTERIUM DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed
EP-0120208-A2 Microbiologically produced L-phenylalanin-dehydrogenase, process for obtaining it and its use Degussa Aktiengesellschaft (DE) 1984-10-03 EP disclosed