Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514441 | 0.92 | CYP2C9 (0.53) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3515468 | 0.89 | CYP2C9 (0.74) | CYP2C9CYP1A2CYP2C19METAP2LMNA | |
| SCHEMBL4662890 | 0.87 | CYP2C9 (0.71) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3512984 | 0.84 | CYP2C9 (0.90) | CYP2C9CYP1A2CYP2C19METAP2LMNA | |
| SCHEMBL14075394 | 0.83 | CYP2C9 (0.78) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3511645 | 0.81 | CYP2C9 (0.52) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3511640 | 0.81 | CYP2C9 (0.52) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3511632 | 0.80 | CYP2C9 (0.60) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3511540 | 0.80 | CYP2C9 (0.60) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3513665 | 0.79 | CYP2C9 (0.82) | CYP2C9CYP1A2CYP2C19METAP2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005177-A1 | A HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM | Tibotec Pharmaceuticals Ltd. (IE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113337-A1 | A HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-10-11 | — | — | WO | disclosed |