Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | METAP2 | P50579 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512989 | 0.91 | CYP2C9 (0.58) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3513665 | 0.88 | CYP2C9 (0.82) | CYP2C9CYP1A2CYP2C19METAP2GFER | |
| SCHEMBL3512984 | 0.88 | CYP2C9 (0.90) | CYP2C9CYP1A2CYP2C19METAP2LMNA | |
| SCHEMBL14075394 | 0.87 | CYP2C9 (0.78) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL4660339 | 0.87 | CYP2C9 (0.65) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3511540 | 0.84 | CYP2C9 (0.60) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL13034761 | 0.82 | CYP2C9 (0.84) | CYP2C9CYP1A2CYP2C19METAP2POLB | |
| SCHEMBL5955445 | 0.82 | CYP2C9 (0.84) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL14075315 | 0.82 | CYP2C9 (0.65) | CYP2C9CYP1A2CYP2C19METAP2MAPT | |
| SCHEMBL3513537 | 0.81 | CYP2C9 (0.79) | CYP2C9CYP1A2CYP2C19METAP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005177-A1 | A HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM | Tibotec Pharmaceuticals Ltd. (IE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113337-A1 | A HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-10-11 | — | — | WO | disclosed |