Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | CASP7 | P55210 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | CASP1 | P29466 | 2/20 | 0.78 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572859 | 0.88 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL278729 | 0.88 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL30646327 | 0.75 | SMN1; SMN2 (0.73) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL30704451 | 0.75 | SMN1; SMN2 (0.73) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL824397 | 0.75 | SMN1; SMN2 (0.73) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL824357 | 0.75 | SMN1; SMN2 (0.73) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL278691 | 0.74 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL9436882 | 0.74 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL8832011 | 0.74 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2CASP7TP53 | |
| SCHEMBL8832035 | 0.74 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2CASP7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004847-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | Pentabase Aps (DK) | 2008-12-24 | — | — | EP | claimed |
| WO-2007104318-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2007-09-20 | — | — | WO | claimed |
| EP-1468007-A2 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | Human Genetic Signatures PTY Ltd. (AU) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003052134-A2 | OLIGONUCLEOTIDES COMPRISING INTERCALATOR PSEUDONUCLEOTIDE(S) FOR DETECTION OF NUCLEIC ACIDS AND MUTANTS HEREOF | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003052133-A2 | OLIGONUCLEOTIDE ANALOGUES COMPRISING INTERCALATOR PSEUDONUCLEOTIDES | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003052132-A2 | LINEAR AND HAIRPIN OLIGONUCLEOTIDE ANALOGUES COMPRISING INTERCALATOR PSEUDONUCLEOTIDES | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051901-A2 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |