Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890771 | 0.90 | ENPP2 (0.86) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL14891635 | 0.89 | ENPP2 (0.87) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL14891076 | 0.86 | ENPP2 (0.70) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL14891590 | 0.86 | ENPP2 (0.67) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL14890973 | 0.84 | ENPP2 (0.98) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL46294 | 0.82 | ENPP2 (1.00) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL14890870 | 0.80 | ENPP2 (0.68) | ENPP2PTGDR2 | |
| SCHEMBL14892028 | 0.79 | ENPP2 (0.69) | ENPP2PTGDR2 | |
| SCHEMBL46564 | 0.79 | ENPP2 (0.81) | ENPP2HDAC6HDAC1PTGDR2 | |
| SCHEMBL18597409 | 0.79 | ENPP2 (0.81) | ENPP2HDAC6HDAC1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005227-A1 | TETRAHYDROCARBOLINE DERIVATIVE | 小野薬品工業株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |