Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31008663 | 0.82 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL23869463 | 0.80 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL19185637 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL7964457 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL21560894 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28183009 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL22016092 | 0.74 | ALDH1A1 (0.50) | ALDH1A1ARVDR | |
| SCHEMBL18159703 | 0.74 | ALDH1A1 (0.50) | ALDH1A1ARVDR | |
| SCHEMBL7964455 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL29291888 | 0.73 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004193-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | Merck & Co., Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007108968-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2007-09-27 | — | — | WO | disclosed |