⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628124 | 0.87 | — | — | |
| Bromide SCHEMBL31522771 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL28504855 | 0.80 | — | — | |
| Propene SCHEMBL11415440 | 0.71 | — | — | |
| Benzene SCHEMBL28417806 | 0.71 | TP53 (0.33) | — | |
| Phosphoramidic Acid SCHEMBL29992750 | 0.64 | CA2 (0.36) | — | |
| SCHEMBL3069011 | 0.62 | — | — | |
| SCHEMBL7660252 | 0.62 | — | — | |
| SCHEMBL11428327 | 0.62 | — | — | |
| Ethylene SCHEMBL22582369 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4086250-B1 | MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND MTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2024-12-11 | — | — | EP | claimed |
| US-20240374569-A1 | HDAC3 INHIBITORS FOR THE TREATMENT OF LANGERHANS CELL HISTIOCYTOSIS AND LANGERHANS CELL SARCOMA | HENRY FORD HEALTH SYSTEM | 2024-11-14 | — | — | US | claimed |
| WO-2023049798-A1 | HDAC3 INHIBITORS FOR THE TREATMENT OF LANGERHANS CELL HISTIOCYTOSIS AND LANGERHANS CELL SARCOMA | HENRY FORD HEALTH SYSTEM (US) | 2023-03-30 | — | — | WO | claimed |
| US-20200289662-A1 | ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE | LEGOCHEM BIOSCIENCES, INC. (KR) | 2020-09-17 | — | — | US | claimed |
| US-10583197-B2 | Antibody-active agent conjugates and methods of use | LEGOCHEM BIOSCIENCES, INC. (KR) | 2020-03-10 | — | — | US | claimed |
| CN-110167586-A | Duplication-defective arenavirus particle and three-segment arenavirus particles as cancer vaccine | 霍欧奇帕生物科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-110099682-A | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-104411332-B | Human antibody in conjunction with VEGFR2 | 索伦托治疗有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108136038-A | Conjugates comprising peptide groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-105273368-B | A kind of expandable PET resin and its production and use | 华东理工大学 | 2018-04-03 | — | — | CN | claimed |
| CN-1479630-A | Methods of inducing cancer cell death and tumor regression | Q | 2004-03-03 | — | — | CN | claimed |
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | claimed |
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | LUITPOLD PHARMACEUTICALS, INC. | 2002-11-07 | — | — | US | claimed |
| CN-1364084-A | Method of inducing cancer cell death and tumor regression | SCHERING CORP (US) | 2002-08-14 | — | — | CN | claimed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| CN-1255164-A | Modified antisense nucleotides complementary to human Ha-ras gene segments | HOECHST MARION & ROUSSEL DEUTS (DE) | 2000-05-31 | — | — | CN | claimed |
| EP-0316440-B1 | System and method for providing localized Mössbauer absorption in an organic medium | MILLS RANDELL L (US) | 1996-01-03 | — | — | EP | claimed |
| EP-0419890-A2 | Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method | AMERICAN CYANAMID COMPANY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0019167-B1 | MEDICINAL PREPARATION FOR THE TREATMENT OF CARCINOMA AND PROCESS FOR PREPARING IT | Limburg, Hans, Dr. (DE) | 1983-10-12 | — | — | EP | claimed |