SCHEMBL466160

SCHEMBL466160

CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(=O)C2c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
CYP19A1 P11511 1/20 0.35
SIRT1 Q96EB6 1/20 0.34
CYP3A4 P08684 3/20 0.34
CYP1A2 P05177 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 2/20 0.34
TP53 P04637 2/20 0.34
MAPK1 P28482 1/20 0.34
HTR2B P41595 1/20 0.34
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
KIF11 P52732 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31247883 1.00 GAA (0.46) GAAGABBR2GABBR1CYP19A1SIRT1
SCHEMBL2612424 0.92 GAA (0.39) GAAGABBR2GABBR1CYP19A1CYP3A4
SCHEMBL2612420 0.90 GABBR2 (0.41) GAAGABBR2GABBR1MAPTALDH1A1
SCHEMBL1232621 0.88 GAA (0.42) GAAGABBR2GABBR1MAPTLMNA
SCHEMBL5083413 0.87 GABBR2 (0.43) GAAGABBR2GABBR1
SCHEMBL10135353 0.87 GAA (0.42) GAAGABBR2GABBR1CYP19A1MAPT
SCHEMBL12901626 0.86 GABBR2 (0.39) GAAGABBR2GABBR1MAPTALDH1A1
SCHEMBL29478047 0.86 GABBR2 (0.41) GAAGABBR2GABBR1LMNAALDH1A1
SCHEMBL30132965 0.86 GABBR2 (0.41) GAAGABBR2GABBR1LMNAALDH1A1
SCHEMBL493693 0.86 GABBR2 (0.41) GAAGABBR2GABBR1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1726026-B Antioxidants for Fats, Oils and Foods CIBA SC HOLDING AG 2010-06-16 CN claimed
CN-101351531-A Stabilized biodiesel fuel compositions CIBA HOLDING INC (CH) 2009-01-21 CN claimed
US-20070151143-A1 Stabilized biodiesel fuel compositions CIBA SPECIALTY CHEMICALS CORP. 2007-07-05 US claimed
US-20060051478-A1 Antioxidant for fats,oils and food CIBA SPECIALTY CHEMICALS CORP. 2006-03-09 US claimed
CN-1726026-A Antioxidants for Fats, Oils and Foods CIBA SC HOLDING AG (CH) 2006-01-25 CN claimed
EP-1571928-A2 ANTIOXIDANT FOR FATS, OILS AND FOOD Ciba SC Holding AG (CH) 2005-09-14 EP claimed
WO-2004055141-A2 ANTIOXIDANT FOR FATS, OILS AND FOOD CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-01 WO claimed
US-6521681-B1 Phenol-free stabilization of polyolefin fibres CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-18 US claimed
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US claimed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO claimed
EP-0891989-A1 Modified polymers containing methylene groups PCD Polymere AG (AT) 1999-01-20 EP claimed
JP-63156834-A None JP disclosed
CN-115362142-B Use of substituted cinnamic acid esters as stabilizers for organic materials, stabilized organic materials, method for stabilizing organic materials and specific cinnamic acid esters 弗劳恩霍夫应用研究促进协会 2024-08-20 CN disclosed
CN-115461396-B Additive composition and use thereof, condensation polymer composition, molding compound prepared from same and molded part and use thereof 弗劳恩霍夫应用研究促进协会 2024-07-12 CN disclosed
CN-114181249-A Derivatives of bisacylphosphinic acids, their preparation and their use as photoinitiators IGM集团公司 2022-03-15 CN disclosed
CN-1172176-A Phenol-free stabilization of polyolefin fibres CIBA SC HOLDING AG (CH) 1998-02-04 CN disclosed
US-5607624-A Process for the preparation of 3-arylbenzofuranones CIBA-GEIGY CORPORATION (US) 1997-03-04 US disclosed
CN-1111627-A Process for the preparation of 3-arylbenzofuranone CIBA GEIGY AG (CH) 1995-11-15 CN disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
JP-S63156834-A DRAWN AND MOLDED ARTICLE MITSUI PETROCHEM IND LTD 1988-06-29 JP disclosed