Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9859865 | 0.98 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL10878554 | 0.98 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL9859859 | 0.98 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1462915 | 0.97 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL10878550 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL11789517 | 0.93 | ESR2 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL14600169 | 0.91 | ESR2 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL791699 | 0.89 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27420551 | 0.89 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3746306 | 0.89 | CA1 (0.48) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874155-A | Benzyl thiazolamine compounds and preparation method and anti-tumor application thereof | 华南理工大学 | 2022-08-09 | — | — | CN | claimed |
| CN-115010645-A | Preparation method of melatonin | 广西师范大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-114874155-A | Benzyl thiazolamine compounds and preparation method and anti-tumor application thereof | 华南理工大学 | 2022-08-09 | — | — | CN | disclosed |
| US-20200139676-A1 | HEAT RAY-SCREENING MATERIAL, INTERLAYER FOR LAMINATED GLASS, AND LAMINATED GLASS | FUJIFILM CORPORATION (JP) | 2020-05-07 | — | — | US | disclosed |
| CN-106574067-B | Laminated polyester film, method for producing same, protective sheet for solar cell, and solar cell module | 富士胶片株式会社 | 2020-01-10 | — | — | CN | disclosed |
| US-20180158974-A1 | SOLAR CELL REAR SURFACE PROTECTIVE SHEET AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2018-06-07 | — | — | US | disclosed |
| CN-107851677-A | Backside protective sheet and solar module used for solar batteries | 富士胶片株式会社 | 2018-03-27 | — | — | CN | disclosed |
| EP-3279948-A1 | TRANSPARENT SHEET FOR SOLAR CELLS, TRANSPARENT BACK SHEET FOR SOLAR CELLS, AND SOLAR CELL MODULE | FUJIFILM Corporation (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20180019353-A1 | TRANSPARENT SHEET FOR SOLAR CELL, TRANSPARENT BACK SHEET FOR SOLAR CELL, AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2018-01-18 | — | — | US | disclosed |
| US-20170129231-A1 | LAMINATED POLYESTER FILM AND A PRODUCTION METHOD THEREOF, SOLAR CELL PROTECTIVE SHEET, AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2017-05-11 | — | — | US | disclosed |
| US-5962740-A | Processes for producing 4,6-bis (substituted)phenylazoresorcinols | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0247970-B1 | BENZANTHRONE LACTONES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| US-4740604-A | HYDRAZONE DYE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0247970-A1 | Benzanthrone lactones, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1987-12-02 | — | — | EP | disclosed |
| US-4605697-A | N3NDIFFUSING | EASTMAN KODAK COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4515940-A | REACTING ARYLDIAZONIUM SALTS WITH ALKALI OR ALKALINE EARTH METAL SULFITES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| EP-0068338-B1 | Process for preparing phenyldiazosulphonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-12 | — | — | EP | disclosed |
| EP-0068338-A1 | Process for preparing phenyldiazosulphonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4258120-A | DIFFUSION TRANSFER, REDOX RELEASER | EASTMAN KODAK COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |