Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654 | 0.87 | IDO1 (0.69) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL1941923 | 0.82 | IDO1 (0.53) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL29364891 | 0.82 | IDO1 (0.62) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL585111 | 0.82 | IDO1 (0.62) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL16269056 | 0.82 | IDO1 (0.62) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL2473227 | 0.80 | IDO1 (0.54) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL15554320 | 0.80 | IDO1 (0.39) | IDO1ALDH1A1 | |
| SCHEMBL28384840 | 0.80 | IDO1 (0.66) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL3166142 | 0.80 | IDO1 (0.60) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL6889926 | 0.79 | IDO1 (0.64) | IDO1TAAR1ABCB1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144717-A1 | NEW PLEUROMUTILIN ANTIBIOTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE AND SYNTHESIS | YALE UNIVERSITY (US) | 2018-08-09 | — | — | WO | disclosed |
| EP-2004618-A1 | TELOMERASE INHIBITORS | Imperial Innovations Limited (GB) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007128968-A1 | TELOMERASE INHIBITORS | IMPERIAL INNOVATIONS LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |