SCHEMBL26654

SCHEMBL26654

COc1ccccc1COCc1ccccc1OC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.69
TAAR1 Q96RJ0 1/20 0.57
CHRM2 P08172 4/20 0.55
CHRM1 P11229 1/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
ABCB1 P08183 1/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA14 Q9ULX7 1/20 0.55
ALDH1A1 P00352 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
SIGMAR1 Q99720 1/20 0.50
AOC3 Q16853 1/20 0.50
GRIN1 Q05586 3/20 0.48
GRIN2A Q12879 3/20 0.48
BCHE P06276 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585111 0.89 IDO1 (0.62) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL29364891 0.89 IDO1 (0.62) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL16269056 0.89 IDO1 (0.62) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL3166142 0.87 IDO1 (0.60) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL28384840 0.87 IDO1 (0.66) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL4661995 0.87 IDO1 (0.60) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL31048 0.86 IDO1 (0.69) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL10607688 0.86 IDO1 (0.69) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL31290863 0.86 IDO1 (0.69) IDO1TAAR1CHRM2CHRM1CA1
SCHEMBL17230506 0.86 IDO1 (0.58) IDO1TAAR1CHRM2CHRM1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240141362-A1 MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY UNIV MASSACHUSETTS (US) 2024-05-02 US claimed
US-11820985-B2 Modified oligonucleotides with increased stability UNIVERSITY OF MASSACHUSETTS (US) 2023-11-21 US claimed
EP-4203940-A1 METHODS TO PRODUCE VERY LONG CHAIN FATTY ACIDS (VLCFA) The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) 2023-07-05 EP claimed
EP-3946369-A2 MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY University Of Massachusetts (US) 2022-02-09 EP claimed
CN-112175265-A Modified color master batch and preparation method thereof 方少山 2021-01-05 CN claimed
US-20200385740-A1 MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY UNIVERSITY OF MASSACHUSETTS 2020-12-10 US claimed
EP-3746509-A1 BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES HRL Laboratories, LLC (US) 2020-12-09 EP claimed
WO-2020198509-A2 MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY UNIVERSITY OF MASSACHUSETTS (US) 2020-10-01 WO claimed
US-20200079718-A1 Menaquinol Compositions and Methods of Treatment Epizon Pharma, Inc. (US) 2020-03-12 US claimed
CN-106573904-B Method for generating beraprost and its derivative 朗格生物技术公共公益股份有限公司 2019-11-08 CN claimed
EP-1893571-A2 PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES Microbia Inc. (US) 2008-03-05 EP claimed
EP-1885703-A2 PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES Microbia, Inc. (US) 2008-02-13 EP claimed
CN-100355772-C Steroid compound with 5-alpha reductase active and preparation process thereof UNIV TIANJIN (CN) 2007-12-19 CN claimed
WO-2006127893-A2 PROCESSES FOR PRODUCTION OF 4-(BIPHENYLYL)AZETIDIN-2-ONE PHOSPHONIC ACIDS MICROBIA, INC. (US) 2006-11-30 WO claimed
WO-2006122020-A2 PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES MICROBIA, INC. (US) 2006-11-16 WO claimed
WO-2006122216-A2 PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES MICROBIA, INC. (US) 2006-11-16 WO claimed
CN-1793164-A Steroid compound with 5-alpha reductase active and preparation process thereof UNIV TIANJIN (CN) 2006-06-28 CN claimed
EP-0781293-A4 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES HIATT ANDREW C ROSE HIATT BIOT (US) 1999-05-26 EP claimed
EP-0781293-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES Hiatt, Andrew C. (US) 1997-07-02 EP claimed
WO-1996007669-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES ROSE-HIATT BIOTECHNOLOGY PARTNERSHIP (US) 1996-03-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079718-A1 Menaquinol Compositions and Methods of Treatment SDHA, SDHB, NDUFB7 IDO1 3891/4885TAAR1 4422/4885CHRM2 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.