Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659340 | 0.83 | FFAR1 (0.43) | ACACBPPARD | |
| SCHEMBL4660623 | 0.83 | FFAR1 (0.43) | ACACBPPARD | |
| SCHEMBL1295883 | 0.79 | MAOA (0.47) | PARP15PARP10PARP2 | |
| SCHEMBL1295416 | 0.79 | MAOA (0.47) | PARP15PARP10PARP2 | |
| SCHEMBL1295412 | 0.79 | MAOA (0.47) | PARP15PARP10PARP2 | |
| SCHEMBL4660537 | 0.79 | PPARD (0.45) | ACACBPPARGPPARDPPARA | |
| SCHEMBL4661933 | 0.79 | PPARD (0.45) | ACACBPPARGPPARDPPARA | |
| SCHEMBL12108111 | 0.75 | PARP15 (0.48) | PARP15PARP10PARP2ACACBTDP1 | |
| SCHEMBL13412904 | 0.74 | PARP15 (0.58) | PARP15PARP10PARP2ACACB | |
| SCHEMBL29024848 | 0.74 | PARP15 (0.64) | PARP15PARP10PARP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | claimed |