Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.78 |
| ▸ | ACHE | P22303 | 3/20 | 0.66 |
| ▸ | RAD52 | P43351 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821540 | 0.95 | HRH3 (0.86) | HRH3ACHERAD52 | |
| SCHEMBL2821210 | 0.93 | HRH3 (0.85) | HRH3ACHERAD52 | |
| SCHEMBL2823878 | 0.91 | HRH3 (0.84) | HRH3ACHERAD52 | |
| SCHEMBL2820804 | 0.89 | HRH3 (0.82) | HRH3ACHERAD52 | |
| SCHEMBL12061359 | 0.88 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL7999523 | 0.88 | HRH3 (0.78) | HRH3ACHERAD52 | |
| SCHEMBL2823988 | 0.88 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL12061373 | 0.83 | HRH3 (0.90) | HRH3ACHERAD52 | |
| SCHEMBL12050749 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL4089206 | 0.82 | HRH3 (1.00) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007735-A1 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007122156-A9 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007122156-A1 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |