Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | ADM2 | Q7Z4H4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921079 | 0.83 | BRD4 (0.46) | CALCRLMAP2K2 | |
| SCHEMBL1921018 | 0.83 | BRD4 (0.46) | CALCRLMAP2K2 | |
| SCHEMBL16624586 | 0.83 | CALCRL (0.53) | CALCRLMAP2K2 | |
| SCHEMBL13192493 | 0.81 | CALCRL (0.43) | CALCRLMAP2K2ADM2 | |
| SCHEMBL378986 | 0.81 | CALCRL (0.46) | CALCRLMAP2K2 | |
| SCHEMBL1394328 | 0.81 | CALCRL (0.46) | CALCRLMAP2K2 | |
| SCHEMBL1274913 | 0.81 | CALCRL (0.46) | CALCRLMAP2K2 | |
| SCHEMBL15401458 | 0.78 | CALCRL (0.46) | CALCRLMAP2K2ADM2 | |
| SCHEMBL1394805 | 0.78 | TDP2 (0.47) | CALCRL | |
| SCHEMBL15400764 | 0.78 | CALCRL (0.46) | CALCRLMAP2K2ADM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608627-B1 | BICYCLIC ANILIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2008-05-07 | — | — | EP | disclosed |