⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28177610 | 0.97 | — | — | |
| Water SCHEMBL28269400 | 0.97 | — | — | |
| SCHEMBL27738671 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29838166 | 0.97 | — | — | |
| SCHEMBL7444319 | 0.67 | — | — | |
| SCHEMBL4697913 | 0.67 | — | — | |
| SCHEMBL27331102 | 0.67 | — | — | |
| SCHEMBL28229477 | 0.67 | — | — | |
| SCHEMBL25515908 | 0.67 | — | — | |
| SCHEMBL30507521 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007731-A2 | PROCESS FOR THE PREPARATION OF CAPROLACTAM CGRP ANTAGONIST INTERMEDIATE | Merck & Co., Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| WO-2007120589-A2 | PROCESS FOR THE PREPARATION OF CAPROLACTAM CGRP ANTAGONIST INTERMEDIATE | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | claimed |
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | claimed |
| EP-0496306-B1 | Process for the preparation of 3-amino-9,13b-dihydro-1H-dibenz-[c,f]imidazo[1,5-a]azepine hydrochloride | BOEHRINGER INGELHEIM KG (DE) | 1995-09-13 | — | — | EP | claimed |
| CN-119462659-A | Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113874079-B | Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof | 吉利德科学公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118684662-A | Pyrrolopyridone-containing compounds | 正大天晴药业集团股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-4125874-A1 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-111566107-A | Compounds of N- (9,13b-dihydro-1H-dibenzo [ c, f ] imidazo [1,5-a ] azepin-3-yl) -2-hydroxybenzamide and 2- ((9,13b-dihydro-1H-dibenzo [ c, f ] imidazo [1,5-a ] azepin-3-yl) carbamoyl) phenylacetate, processes for their preparation and anti-inflammatory and analgesic agents comprising the same | 先生株式会社 | 2020-08-21 | — | — | CN | disclosed |
| EP-2977378-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2020-06-10 | — | — | EP | disclosed |
| CN-109311818-A | Novel pyridone carboxylic acid derivatives or its salt | 湧永制药株式会社 | 2019-02-05 | — | — | CN | disclosed |
| EP-0572560-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO, Howard, K. (US) | 1993-12-08 | — | — | EP | disclosed |
| WO-1992014456-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 1992-09-03 | — | — | WO | disclosed |
| EP-0275759-B1 | SUBSTITUTED 3-PIPERIDINE AMINES OR 3-AZEPIN AMINES, THEIR PREPARATION AND THERAPEUTIC USES | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1992-01-29 | — | — | EP | disclosed |
| EP-0275759-B1 | SUBSTITUTED 3-PIPERIDINE AMINES OR 3-AZEPIN AMINES, THEIR PREPARATION AND THERAPEUTIC USES | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1992-01-29 | — | — | EP | disclosed |
| US-4822792-A | CARDIOVASCULAR DISRODERS | RIOM LABORATOIRES C.E.R.M. (FR) | 1989-04-18 | — | — | US | disclosed |
| US-4822792-A | CARDIOVASCULAR DISRODERS | RIOM LABORATOIRES C.E.R.M. (FR) | 1989-04-18 | — | — | US | disclosed |
| EP-0275759-A1 | Substituted 3-piperidine amines or 3-azepin amines, their preparation and therapeutic uses | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1988-07-27 | — | — | EP | disclosed |
| EP-0275759-A1 | Substituted 3-piperidine amines or 3-azepin amines, their preparation and therapeutic uses | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1988-07-27 | — | — | EP | disclosed |