Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072799 | 0.95 | TSHR (0.60) | NR5A1TP53TSHRALDH1A1CYP3A4 | |
| SCHEMBL8077529 | 0.87 | SMN1; SMN2 (0.60) | TP53TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8912396 | 0.85 | SMN1; SMN2 (0.63) | TP53TSHRCYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL9270936 | 0.84 | NR5A1 (0.58) | NR5A1TP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1667493 | 0.84 | NR5A1 (0.58) | NR5A1TP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15018829 | 0.84 | NR5A1 (0.58) | NR5A1TP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6872219 | 0.84 | NR5A1 (0.58) | NR5A1TP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12088447 | 0.82 | NR5A1 (0.55) | NR5A1TP53TSHRALDH1A1SMN1; SMN2 | |
| Ethylene SCHEMBL28261436 | 0.81 | NR5A1 (0.73) | NR5A1TP53TSHRALOX15NPC1 | |
| SCHEMBL5473083 | 0.81 | NR5A1 (0.79) | NR5A1TP53TSHRALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694335-A4 | OSTEOCLASTOGENESIS INHIBITORS AND USES THEREOF | RES DEV FOUNDATION (US) | 2008-12-31 | — | — | EP | disclosed |
| EP-1694335-A2 | OSTEOCLASTOGENESIS INHIBITORS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2006046934-A2 | OSTEOCLASTOGENESIS INHIBITORS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2006-05-04 | — | — | WO | disclosed |