Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072799 | 0.92 | TSHR (0.60) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL4662932 | 0.87 | NR5A1 (0.56) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL627031 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL8912079 | 0.84 | MAPT (0.60) | SMN1; SMN2CYP3A4TSHRLMNAL3MBTL1 | |
| SCHEMBL23269519 | 0.83 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL7166779 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL27792511 | 0.82 | LMNA (0.50) | SMN1; SMN2ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL6869710 | 0.82 | LMNA (0.54) | SMN1; SMN2ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL9811776 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL8070952 | 0.81 | LMNA (0.54) | SMN1; SMN2ALDH1A1CYP3A4LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104769038-B | Polycarbonate resin composition and molded article | 出光兴产株式会社 | 2017-06-30 | — | — | CN | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |