Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | ACP1 | P24666 | 4/20 | 0.35 |
| ▸ | CDC25B | P30305 | 4/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664703 | 0.90 | HTR2A (0.37) | HTR2ACHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4665125 | 0.84 | PTPN1 (0.35) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4664757 | 0.81 | MAPT (0.39) | HTR2AHRH1MAPTPTPN1ACP1 | |
| SCHEMBL4663032 | 0.78 | PTPN1 (0.40) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4664751 | 0.75 | CDC25B (0.43) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4666814 | 0.75 | PTPN1 (0.33) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4664770 | 0.73 | PTPN1 (0.39) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4663317 | 0.73 | PTPN1 (0.44) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL4662974 | 0.73 | ALOX5 (0.45) | HTR2AHTR2CMAPTPTPN1ACP1 | |
| SCHEMBL4665112 | 0.72 | HPGD (0.39) | MAPTPTPN1ACP1CDC25BRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | claimed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | claimed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | HTR2A 2974/4885CHRM1 36/4885DRD2 3357/4885 |
| US-20050119329-A1 | Tetronic and tetramic acids | BACE1, PSEN1, BACE2 | HTR2A 2974/4885CHRM1 36/4885DRD2 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.