Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663049 | 0.83 | NR0B1 (0.38) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28557461 | 0.77 | NR0B1 (0.52) | GAALMNANR0B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4241441 | 0.77 | NR0B1 (0.48) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4663019 | 0.76 | NR0B1 (0.44) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4244260 | 0.74 | KMT2A (0.54) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4664885 | 0.74 | NR0B1 (0.43) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4664683 | 0.74 | NR0B1 (0.45) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4662961 | 0.73 | SMN1; SMN2 (0.41) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6028102 | 0.72 | GAA (0.47) | GAALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4664915 | 0.72 | NPC1 (0.48) | LMNANR0B1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | claimed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | claimed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | GAA 70/4885LMNA 1625/4885NR0B1 106/4885 |
| US-20050119329-A1 | Tetronic and tetramic acids | BACE1, PSEN1, BACE2 | GAA 70/4885LMNA 1625/4885NR0B1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.