Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR0B1 | P51843 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664683 | 0.87 | NR0B1 (0.45) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4664915 | 0.85 | NPC1 (0.48) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4244260 | 0.85 | KMT2A (0.54) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4664885 | 0.85 | NR0B1 (0.43) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4246713 | 0.84 | NR0B1 (0.64) | NR0B1POLB | |
| SCHEMBL4663019 | 0.82 | NR0B1 (0.44) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4663204 | 0.82 | NR0B1 (0.44) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13744418 | 0.81 | NPC1 (0.40) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4663288 | 0.81 | EPHX1 (0.43) | NR0B1LMNASMN1; SMN2POLB | |
| SCHEMBL4664917 | 0.81 | NR0B1 (0.46) | NR0B1LMNASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NR0B1 2001/4885LMNA 2709/4885SMN1; SMN2 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.